---
title: "DC 7539 - Renal amyloid disease"
diagnostic_code: "7539"
body_system: "Genitourinary System"
cfr_section: "§ 4.115b"
canonical: "https://veteranai.co/va-rating-schedule/genitourinary/7539-renal-amyloid-disease"
source: "https://www.ecfr.gov/current/title-38/section-4.115b"
updated: "2026-07-21T20:59:10.199975Z"
---

# DC 7539 - Renal amyloid disease

Rated under § 4.115b. Body system: Genitourinary System.

Rate as renal dysfunction.

## Rating criteria

No itemised criteria have been extracted for this code. Use the official source.

## Notes

- Note: This diagnostic code pertains to renal involvement secondary to all glomerulonephritis conditions, all vasculitis conditions and their derivatives, and other renal conditions caused by systemic diseases, such as Lupus erythematosus, systemic lupus erythematosus nephritis, Henoch-Schonlein syndrome, scleroderma, hemolytic uremic syndrome, polyarthritis, Wegener's granulomatosis, Goodpasture's syndrome, and sickle cell disease.
- Note: When evaluating any claim involving loss or loss of use of one or more creative organs, refer to § 3.350 of this chapter to determine whether the veteran may be entitled to special monthly compensation. Footnotes in the schedule indicate conditions which potentially establish entitlement to special monthly compensation; however, there are other conditions in this section which under certain circumstances also establish entitlement to special monthly compensation.

# Renal Amyloid Disease (VA Diagnostic Code 7539)

**VA Disability Rating Schedule — Genitourinary System**
*Governed by 38 CFR § 4.115b*

---

## What Is Renal Amyloid Disease?

Renal amyloid disease refers to kidney involvement resulting from certain systemic conditions. Under the VA rating schedule, Diagnostic Code 7539 is used to evaluate renal (kidney) conditions and is rated as **renal dysfunction**.

According to the VA's notes, this diagnostic code pertains to renal involvement secondary to:

- All glomerulonephritis conditions
- All vasculitis conditions and their derivatives
- Other renal conditions caused by systemic diseases, such as:
  - Lupus erythematosus
  - Systemic lupus erythematosus nephritis
  - Henoch-Schönlein syndrome
  - Scleroderma
  - Hemolytic uremic syndrome
  - Polyarthritis
  - Wegener's granulomatosis
  - Goodpasture's syndrome
  - Sickle cell disease

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## How the VA Rates This Condition

For Diagnostic Code 7539, the VA instructs raters to **rate the condition as renal dysfunction**. This means the evaluation is based on the criteria the VA uses for renal dysfunction rather than a standalone rating formula specific to this code.

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## What the VA Looks For

- **Renal (kidney) function.** Because this code is rated as renal dysfunction, the VA's assessment centers on how the condition affects kidney function.
- **Underlying systemic disease.** This diagnostic code applies specifically to renal involvement that is secondary to the glomerulonephritis, vasculitis, and systemic disease conditions listed in the VA's notes.

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## A Note on Special Monthly Compensation

The VA's notes state that **when evaluating any claim involving loss or loss of use of one or more creative organs**, § 3.350 of this chapter should be referenced to determine whether the veteran may be entitled to **special monthly compensation (SMC)**.

The VA notes that footnotes in the schedule indicate conditions which potentially establish entitlement to special monthly compensation; however, there are other conditions in this section which, under certain circumstances, also establish such entitlement.

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*This information is drawn directly from the VA rating schedule (Diagnostic Code 7539, 38 CFR § 4.115b) and is provided for general educational purposes. It does not constitute legal advice and does not guarantee any particular rating or outcome. For questions about your specific situation, consult an accredited representative or the VA.*

Source: https://www.ecfr.gov/current/title-38/section-4.115b